What Are the Latest Treatment Options for Macular Degeneration?

April 30, 2025

Macular degeneration is one of the leading causes of vision loss, particularly in older adults. As research advances, new treatments continue to emerge, offering hope for those diagnosed with this condition. In this blog, we’ll explore the latest treatment options for age-related macular degeneration (AMD) and how they are transforming eye care.

Understanding Macular Degeneration

Macular degeneration affects the macula, the central part of the retina responsible for sharp vision. It comes in two primary forms:

Dry AMD (atrophic) – The more common form, characterized by the gradual breakdown of light-sensitive cells in the macula.

Wet AMD (neovascular) – A less common but more severe form that involves abnormal blood vessel growth, leading to rapid vision loss.

While there is currently no cure for macular degeneration, treatments can slow its progression and, in some cases, improve vision.

Latest Treatment Options for Macular Degeneration

1. Anti-VEGF Injections (for Wet AMD)

Anti-vascular endothelial growth factor (anti-VEGF) injections are the most effective treatment for wet AMD. These medications block abnormal blood vessel growth and reduce leakage in the retina. Common anti-VEGF drugs include:

Aflibercept (Eylea)

Ranibizumab (Lucentis)

Brolucizumab (Beovu)

Faricimab (Vabysmo)

Newer medications like Vabysmo require fewer injections while maintaining strong results, making treatment more convenient for patients.

2. Emerging Gene Therapy

Gene therapy is a promising frontier in AMD treatment. Researchers are developing techniques to modify genes in the retina to either prevent or slow down disease progression.


One exciting development is RGX-314, a gene therapy designed to replace frequent anti-VEGF injections with a one-time treatment. If approved, this could revolutionize how we manage wet AMD.

3. Oral Medications and Supplements (for Dry AMD)

Currently, no FDA-approved drugs exist for dry AMD, but nutritional supplements have shown benefits. The AREDS2 formula includes:

Vitamin C

Vitamin E

Zinc

Copper

Lutein

Zeaxanthin

These antioxidants help slow the progression of intermediate AMD and reduce the risk of advanced vision loss.

4. Stem Cell Therapy

Stem cell research offers hope for regenerating damaged retinal cells. Scientists are exploring the potential of implanting lab-grown retinal cells into the eye to restore vision. Clinical trials are ongoing, and the results are promising.

5. Artificial Retina Implants

Advancements in bionic vision technology are leading to the development of artificial retina implants. These implants aim to restore partial sight in patients with severe vision loss by bypassing damaged retinal cells and directly stimulating the optic nerve.

6. Light Therapy (Photobiomodulation)

This noninvasive treatment uses low-level light therapy to reduce inflammation and improve cell function in the retina. Some early studies suggest it may slow the progression of dry AMD.

Lifestyle and Preventative Strategies

Even with advanced treatments, lifestyle choices play a critical role in slowing macular degeneration. Here are some expert recommendations:

Eat a healthy diet – Consume foods rich in omega-3 fatty acids, leafy greens, and colorful fruits and vegetables.

Protect your eyes – Wear UV-blocking sunglasses to prevent retinal damage.

Quit smoking – Smoking is a major risk factor for AMD progression.

Exercise regularly – Physical activity improves circulation and supports eye health.

Monitor vision changes – Regular eye exams can catch AMD early, improving treatment outcomes.

Protecting Your Vision for the Future

The future of macular degeneration treatment is brighter than ever, with groundbreaking therapies on the horizon. If you or a loved one has been diagnosed with AMD, regular eye exams and early intervention are crucial to preserving vision. At Harvey & Lewis Opticians, we offer comprehensive eye exams using advanced imaging technology to detect and monitor macular degeneration. Schedule an appointment today to discuss the best options for maintaining your eye health!